Fig. 2. Inhibition of PTEN expression with bpv increases the migration-associated protein of FLSs. (A) PTEN, MMP-9 and TIMP-1 protein levels were analyzed by western blot in AIA FLSs treated with bpv. (B) PTEN, MMP-9 and TIMP-1 mRNA levels were analyzed by q-PCR in FLSs treated with bpv. All values were expressed as the mean ± SD. ^#P<0.05, ^## P<0.01 vs. normal group; ^*P<0.05, ^**P<0.01 vs. AIA group.